TargetMol

SRI 31215 TFA

Product Code:
 
TAR-T5478
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5478-1mg1mg£119.00
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TAR-T5478-2mg2mg£141.00
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TAR-T5478-5mg5mg£189.00
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TAR-T5478-1mL1 mL * 10 mM (in DMSO)£209.00
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TAR-T5478-10mg10mg£254.00
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TAR-T5478-25mg25mg£439.00
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TAR-T5478-50mg50mg£621.00
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TAR-T5478-100mg100mg£855.00
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This product comes from: United States.
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Further Information

Bioactivity:
SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s of 0.69 μM, 0.65 μM, 0.3 μM,
CAS:
1832686-44-8
Formula:
C29H35F6N5O5
Molecular Weight:
647.619
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9997
SMILES:
OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N
Target:
c-Met/HGFR

References

Owusu BY, et al. Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling. Oncotarget. 2016 May 17;7(20):29492-506.