TargetMol

DMX-5804

Product Code:
 
TAR-T5483
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5483-1mg1mg£157.00
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TAR-T5483-2mg2mg£197.00
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TAR-T5483-5mg5mg£270.00
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TAR-T5483-1mL1 mL * 10 mM (in DMSO)£290.00
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TAR-T5483-10mg10mg£389.00
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TAR-T5483-25mg25mg£603.00
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TAR-T5483-50mg50mg£830.00
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TAR-T5483-100mg100mg£1,099.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
DMX-5804 is a potent, selective MAP4K4 inhibitor, with an IC50 of 3 nM.DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.
CAS:
2306178-56-1
Formula:
C21H19N3O3
Molecular Weight:
361.401
Pathway:
MAPK
Purity:
0.9963
SMILES:
COCCOc1ccc(cc1)-c1cn(-c2ccccc2)c2nc[nH]c(=O)c12
Target:
MAPK

References

Fiedler LR, et al. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo. Cell Stem Cell. 2019 Mar 1. pii: S1934-5909(19)30013-X.