TargetMol

BAY-218

Product Code:
 
TAR-T5622
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5622-1mg1mg£98.00
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Quantity:
TAR-T5622-2mg2mg£107.00
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TAR-T5622-5mg5mg£124.00
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TAR-T5622-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T5622-10mg10mg£164.00
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TAR-T5622-25mg25mg£282.00
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Quantity:
TAR-T5622-50mg50mg£429.00
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TAR-T5622-100mg100mg£603.00
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Quantity:
TAR-T5622-500mg500mg£1,187.00
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This product comes from: United States.
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Further Information

Bioactivity:
AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
CAS:
2162982-11-6
Formula:
C20H17ClFN3O3
Molecular Weight:
401.82
Pathway:
Immunology/Inflammation; Metabolism
Purity:
0.98
SMILES:
C[C@@H](CO)NC(=O)c1cc(nn(-c2cccc(F)c2)c1=O)-c1ccc(Cl)cc1
Target:
AhR; Aryl Hydrocarbon Receptor

References

Ilona Gutcher, Christina Kober, Lars Roese,et al.Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor[J].10.1158/1538-7445.AM2019-1288 Published July 2019.