TargetMol

GSK3326595

Product Code:
 
TAR-T5745
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5745-5mg5mg£104.00
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Quantity:
TAR-T5745-1mL1 mL * 10 mM (in DMSO)£107.00
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Quantity:
TAR-T5745-10mg10mg£117.00
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Quantity:
TAR-T5745-25mg25mg£162.00
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Quantity:
TAR-T5745-50mg50mg£229.00
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Quantity:
TAR-T5745-100mg100mg£367.00
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Quantity:
TAR-T5745-200mg200mg£463.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GSK3326595 is an inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50:6.2 nM.).
CAS:
1616392-22-3
Formula:
C24H32N6O3
Molecular Weight:
452.55
Pathway:
Chromatin/Epigenetic
Purity:
0.9743
SMILES:
CC(=O)N1CCC(CC1)Nc1cc(ncn1)C(=O)NC[C@H](O)CN1CCc2ccccc2C1
Target:
Histone Methyltransferase

References

Gerhart S V , Kellner W A , Christine T , et al. Activation of the p53-MDM4 regulatory axis defines the anti-tumour response to PRMT5 inhibition through its role in regulating cellular splicing[J]. Scientific Reports, 2018, 8(1):9711-.