TargetMol

JMS-17-2

Product Code:
 
TAR-T5849
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5849-1mg1mg£98.00
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TAR-T5849-2mg2mg£109.00
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TAR-T5849-5mg5mg£134.00
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TAR-T5849-1mL1 mL * 10 mM (in DMSO)£141.00
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TAR-T5849-10mg10mg£177.00
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TAR-T5849-25mg25mg£258.00
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TAR-T5849-50mg50mg£362.00
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TAR-T5849-100mg100mg£503.00
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This product comes from: United States.
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Further Information

Bioactivity:
JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).
CAS:
1380392-05-1
Formula:
C25H26ClN3O
Molecular Weight:
419.95
Pathway:
Autophagy; Immunology/Inflammation; GPCR/G Protein
Purity:
0.98
SMILES:
Clc1ccc(cc1)C1CCN(CCCn2c3ccccc3n3cccc3c2=O)CC1
Target:
CXCR

References

Shen F , Zhang Y , Jernigan D L , et al. Novel Small-molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells[J]. Molecular Cancer Research, 2016:1541-7786.MCR-16-0013.