TargetMol

VP3.15 dihydrobromide

Product Code:
 
TAR-T5956
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5956-2mg2mg£102.00
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TAR-T5956-5mg5mg£122.00
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TAR-T5956-1mL1 mL * 10 mM (in DMSO)£130.00
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TAR-T5956-10mg10mg£148.00
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TAR-T5956-25mg25mg£254.00
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TAR-T5956-50mg50mg£389.00
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TAR-T5956-100mg100mg£544.00
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TAR-T5956-500mg500mg£1,099.00
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This product comes from: United States.
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Further Information

Bioactivity:
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM , 0.88 μM,respectively.)
CAS:
1281681-33-1
Formula:
C20H24Br2N4OS
Molecular Weight:
528.31
Pathway:
PI3K/Akt/mTOR signaling; Metabolism; Stem Cells
Purity:
0.98
SMILES:
Br.Br.C(CN1CCOCC1)N=c1nc(-c2ccccc2)n(s1)-c1ccccc1
Target:
GSK-3; PDE

References

Medina-Rodr?guez, Eva Mar?a, Bribi?n, Ana, Boyd A , et al. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis[J]. Scientific Reports, 2017, 7:43545.