TargetMol

Leonurine

Product Code:
 
TAR-T5S2102
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S2102-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T5S2102-20mg20mg£143.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
Leonurine is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.
CAS:
24697-74-3
Formula:
C14H21N3O5
Molecular Weight:
311.338
Pathway:
Autophagy
Purity:
0.98
SMILES:
COc1cc(cc(OC)c1O)C(=O)OCCCCNC(N)=N
Target:
Autophagy

References

Zhang L , Li H X , Pan W S , et al. Novel hepatoprotective role of Leonurine hydrochloride against experimental non-alcoholic steatohepatitis mediated via AMPK/SREBP1 signaling pathway[J]. Biomedicine & Pharmacotherapy, 2019, 110:571-581. Jiang T , Ren K , Chen Q , et al. Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Ppar?/Lxr? Signaling Pathway-Dependent Manner[J]. Cellular Physiology and Biochemistry, 2017:1-1. Jia M , Li C , Zheng Y , et al. Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation[J]. International Journal of Neuropsychopharmacology, 2017. Liu H M, Guo C L, Zhang Y F, et al. Leonurine-repressed miR-18a-5p/SOCS5/JAK2/STAT3 axis activity disrupts CML malignancy[J]. Frontiers in Pharmacology. 2021, 12. Liu H M, Guo C L, Zhang Y F, et al. Leonurine-repressed miR-18a-5p/SOCS5/JAK2/STAT3 axis activity disrupts CML malignancy. Frontiers in Pharmacology. 2021, 12.