TargetMol

Epiberberine

Product Code:
 
TAR-T5S2361
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S2361-1mg1mg£95.00
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TAR-T5S2361-5mg5mg£128.00
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TAR-T5S2361-10mg10mg£148.00
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TAR-T5S2361-25mg25mg£226.00
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TAR-T5S2361-50mg50mg£362.00
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TAR-T5S2361-100mg100mg£481.00
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TAR-T5S2361-500mg500mg£994.00
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Further Information

Bioactivity:
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte differentiation. 3. Epiberberine, as the brightest FSA emitter among the alkaloids, can also serve as an efficient conformation probe for HTG DNA and discriminate the DNA G-quadruplex from the RNA counterpart.
CAS:
6873-09-2
Formula:
C20H18NO4
Molecular Weight:
336.366
Pathway:
Neuroscience; MAPK
Purity:
0.9958
SMILES:
COc1cc2CC[n+]3cc4c5OCOc5ccc4cc3-c2cc1OC
Target:
ERK; Beta-Secretase; MEK; BACE; AChR; AChE

References

Zou Z Y , Hu Y R , Ma H , et al. Epiberberine reduces serum cholesterol in diet-induced dyslipidemia Syrian golden hamsters via network pathways involving cholesterol metabolism.[J]. European Journal of Pharmacology, 2016, 774:1-9.