TargetMol

DPTIP

Product Code:
 
TAR-T60043
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T60043-1mg1mg£103.00
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TAR-T60043-2mg2mg£116.00
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TAR-T60043-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T60043-5mg5mg£148.00
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TAR-T60043-10mg10mg£195.00
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TAR-T60043-25mg25mg£322.00
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TAR-T60043-50mg50mg£483.00
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TAR-T60043-100mg100mg£670.00
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This product comes from: United States.
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Further Information

Bioactivity:
DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.
CAS:
351353-48-5
Formula:
C21H18N2O3S
Molecular Weight:
378.44
Pathway:
Metabolism
Purity:
0.988
SMILES:
OC=1C(OC)=CC(=CC1OC)C2=NC(C=3C=CC=CC3)=C(N2)C=4SC=CC4
Target:
Phospholipase

References

Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330. Camilo Rojas, et al. DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation. Sci Rep. 2018 Dec 7;8(1):17715.