TargetMol

Delanzomib

Product Code:
 
TAR-T6027
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6027-1mg1mg£105.00
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TAR-T6027-2mg2mg£119.00
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TAR-T6027-5mg5mg£156.00
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TAR-T6027-1mL1 mL * 10 mM (in DMSO)£163.00
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TAR-T6027-10mg10mg£234.00
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TAR-T6027-25mg25mg£389.00
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TAR-T6027-50mg50mg£550.00
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TAR-T6027-100mg100mg£734.00
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This product comes from: United States.
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Further Information

Bioactivity:
CEP-18770 is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM). It only marginally inhibits the tryptic and peptidylglutamyl activities of the proteosome.
CAS:
847499-27-8
Formula:
C21H28BN3O5
Molecular Weight:
413.28
Pathway:
Ubiquitination; Proteases/Proteasome; Apoptosis; NF-κb
Purity:
0.9946
SMILES:
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)c1cccc(n1)-c1ccccc1)[C@@H](C)O)B(O)O
Target:
Apoptosis; NF-κB; Proteasome

References

Piva R,et al. Blood. 2008,111(5),2765-2775. Sanchez E, et al. Br J Haematol. 2010,148(4),569-581. Berkers CR, et al. Nat Methods. 2005,2(5),357-362. Chen X, Chen Y, Ou Y, et al. Bortezomib inhibits NLRP3 inflammasome activation and NF-?B pathway to reduce psoriatic inflammation. Biochemical Pharmacology. 2022, 206: 115326.