TargetMol

Cobicistat

Product Code:
 
TAR-T6246
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6246-1mg1mg£101.00
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TAR-T6246-2mg2mg£114.00
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TAR-T6246-5mg5mg£139.00
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TAR-T6246-1mL1 mL * 10 mM (in DMSO)£161.00
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TAR-T6246-10mg10mg£172.00
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TAR-T6246-25mg25mg£250.00
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TAR-T6246-50mg50mg£367.00
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TAR-T6246-100mg100mg£497.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Cobicistat is a carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which it is used in combination, for the treatment of HIV INFECTIONS.
CAS:
1004316-88-4
Formula:
C40H53N7O5S2
Molecular Weight:
776.02
Pathway:
Proteases/Proteasome; Microbiology/Virology; Metabolism
Purity:
0.9962
SMILES:
CC(C)c1nc(CN(C)C(=O)N[C@@H](CCN2CCOCC2)C(=O)N[C@H](CC[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)Cc2ccccc2)cs1
Target:
P45; HIV Protease

References

Yan F, Gao F. An overview of potential inhibitors targeting non-structural proteins 3 (PLpro and Mac1) and 5 (3CLpro/Mpro) of SARS-CoV-2. Computational and Structural Biotechnology Journal. 2021, 19: 4868. Xu L, et al. ACS Med. Chem. Lett, 2010, 1(5), 209-213.