TargetMol

BIX02188

Product Code:
 
TAR-T6324
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6324-1mg1mg£105.00
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TAR-T6324-2mg2mg£119.00
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TAR-T6324-5mg5mg£173.00
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TAR-T6324-1mL1 mL * 10 mM (in DMSO)£188.00
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TAR-T6324-10mg10mg£264.00
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TAR-T6324-25mg25mg£362.00
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TAR-T6324-50mg50mg£508.00
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TAR-T6324-100mg100mg£701.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BIX02188 is a specific MEK5 inhibitor (IC50: 4.3 nM), also inhibits ERK5 catalytic activity (IC50: 810 nM), and does not inhibit closely related kinases MEK1/2, JNK2, and ERK2.
CAS:
1094614-84-2
Formula:
C25H24N4O2
Molecular Weight:
412.48
Pathway:
MAPK; Stem Cells
Purity:
0.9921
SMILES:
CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(N)=O)c1
Target:
ERK; MEK; TGF-beta/Smad

References

Tatake RJ, et al. Biochem Biophys Res Commun, 2008, 377(1), 120-125. Li L, et al. Biochem Biophys Res Commun, 2008, 370(1), 159-163.