TargetMol

BMS-345541

Product Code:
 
TAR-T6326
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6326-1mg1mg£96.00
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TAR-T6326-2mg2mg£107.00
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TAR-T6326-5mg5mg£128.00
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TAR-T6326-1mL1 mL * 10 mM (in DMSO)£146.00
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TAR-T6326-10mg10mg£161.00
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TAR-T6326-25mg25mg£254.00
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TAR-T6326-50mg50mg£369.00
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TAR-T6326-100mg100mg£511.00
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TAR-T6326-200mg200mg£699.00
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This product comes from: United States.
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Further Information

Bioactivity:
BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
CAS:
445430-58-0
Formula:
C14H17N5
Molecular Weight:
255.325
Pathway:
NF-κb
Purity:
0.9929
SMILES:
Cc1cnc2c(NCCN)nc3ccc(C)cc3n12
Target:
IκB/IKK

References

Yang J, et al. Clin Cancer Res, 2006, 12(3 Pt 1), 950-960. Burke JR, et al. J Biol Chem, 2003, 278(3), 1450-1456. Buontempo F, et al. Cell Cycle, 2012, 11(13), 2467-2475. Chen J, Liu G, Wang X, et al. Glioblastoma stem cell-specific histamine secretion drives pro-angiogenic tumor microenvironment remodeling. Cell Stem Cell. 2022 MacMaster JF, et al. Inflamm Res, 2003, 52(12), 508-511. Blazkova H, et al. Cell Cycle, 2007, 6(20), 2531-2540.