TargetMol

NVP-BHG712

Product Code:
 
TAR-T6348
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6348-1mg1mg£95.00
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TAR-T6348-2mg2mg£106.00
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TAR-T6348-5mg5mg£128.00
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TAR-T6348-1mL1 mL * 10 mM (in DMSO)£135.00
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TAR-T6348-10mg10mg£161.00
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TAR-T6348-25mg25mg£250.00
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TAR-T6348-50mg50mg£402.00
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TAR-T6348-100mg100mg£567.00
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Further Information

Bioactivity:
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
CAS:
940310-85-0
Formula:
C26H20F3N7O
Molecular Weight:
503.489
Pathway:
Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9796
SMILES:
Cc1ccc(cc1Nc1nc(nc2n(C)ncc12)-c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F
Target:
Raf; Bcr-Abl; Src; Ephrin Receptor

References

Martiny-Baron G, et al. Angiogenesis. 2010, 13(3), 259-267.