TargetMol

SB273005

Product Code:
 
TAR-T6657
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T6657-2mg2mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6657-5mg5mg£571.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6657-1mL1 mL * 10 mM (in DMSO)£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6657-25mg25mg£1,371.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6657-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
CAS:
205678-31-5
Formula:
C22H24F3N3O4
Molecular Weight:
451.446
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
CNc1cccc(CCOc2ccc3C[C@@H](CC(O)=O)C(=O)N(CC(F)(F)F)Cc3c2)n1
Target:
Integrin

References

Miller WH, et al. J Med Chem. 2000, 43(1), 22-26. Gomes N, et al. Clin Exp Metastasis. 2004, 21(6), 553-561. Badger AM, et al. Arthritis Rheum. 2001, 44(1), 128-137. Rehm S, et al. Toxicol Pathol. 2007, 35(7), 958-971. Wang S, et al. Exp Ther Med. 2014, 7(6), 1677-1682.