TargetMol

Eltrombopag Olamine

Product Code:
 
TAR-T6825
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6825-2mg2mg£101.00
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Quantity:
TAR-T6825-5mg5mg£117.00
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TAR-T6825-10mg10mg£148.00
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TAR-T6825-50mg50mg£222.00
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TAR-T6825-100mg100mg£265.00
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Quantity:
TAR-T6825-200mg200mg£359.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
CAS:
496775-62-3
Formula:
C29H36N6O6
Molecular Weight:
564.643
Pathway:
Proteases/Proteasome
Purity:
0.9994
SMILES:
NCCO.NCCO.CC1=NN(C(=O)C1=N/Nc1cccc(-c2cccc(c2)C(O)=O)c1O)c1ccc(C)c(C)c1
Target:
Thrombin

References

Erickson-Miller CL, et al. Stem Cells, 2009, 27(2), 424-430. Roth M, et al. Blood, 2012, 120(2), 386-394. Erickson-Miller CL, et al. Leuk Res, 2010, 34(9), 1224-1231.