TargetMol

Dauricine

Product Code:
 
TAR-T6S0119
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6S0119-1mg1mg£95.00
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TAR-T6S0119-5mg5mg£122.00
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TAR-T6S0119-10mg10mg£161.00
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TAR-T6S0119-25mg25mg£227.00
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TAR-T6S0119-50mg50mg£306.00
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TAR-T6S0119-100mg100mg£436.00
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TAR-T6S0119-500mg500mg£863.00
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Further Information

Bioactivity:
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profile of its downstream genes.
CAS:
524-17-4
Formula:
C38H44N2O6
Molecular Weight:
624.778
Pathway:
Apoptosis; NF-κb;
Purity:
0.9938
SMILES:
COc1cc2CCN(C)[C@H](Cc3ccc(Oc4cc(C[C@H]5N(C)CCc6cc(OC)c(OC)cc56)ccc4O)cc3)c2cc1OC
Target:
Apoptosis; NF-κB

References

Wang J , Li Y , Zu X B , et al. Dauricine can inhibit the activity of proliferation of urinary tract tumor cells[J]. Asian Pacific Journal of Tropical Medicine, 2012, 5(12):973-976.