TargetMol

Benzoylmesaconine

Product Code:
 
TAR-T6S1885
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6S1885-1mg1mg£106.00
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TAR-T6S1885-5mg5mg£149.00
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TAR-T6S1885-1mL1 mL * 10 mM (in DMSO)£182.00
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TAR-T6S1885-10mg10mg£201.00
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TAR-T6S1885-25mg25mg£290.00
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TAR-T6S1885-50mg50mg£389.00
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TAR-T6S1885-100mg100mg£547.00
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Further Information

Bioactivity:
Benzoylmesaconine is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis. Benzoylmesconine has analgesic activity. Benzoylmesconine may improve the resistance of T6S-mice (or thermally injured mice) to the infection of HSV-1, through the induction of antagonistic CD4+ T cells against burn-associated type-2 T cells.
CAS:
63238-67-5
Formula:
C31H43NO10
Molecular Weight:
589.682
Purity:
0.9978
SMILES:
COC[C@]12CN(C)C3[C@@H]4[C@H](OC)[C@H]1[C@]3([C@@H]1C[C@@]3(O)[C@H](OC(=O)c5ccccc5)[C@@H]1[C@]4(O)[C@@H](O)[C@@H]3OC)[C@H](C[C@H]2O)OC

References

Ye L, et al. Monoester-Diterpene Aconitum Alkaloid Metabolism in Human Liver Microsomes: Predominant Role of CYP3A4 and CYP3A5. Evid Based Complement Alternat Med. 2013;2013:941093. Dai PM, et al. Pharmacokinetic comparisons of benzoylmesaconine in rats using ultra-performance liquid chromatography-tandem mass spectrometry after administration of pure benzoylmesaconine and Wutou decoction. Molecules. 2014 Oct 17;19(10):16757-69. Suzuki Y , Hayakawa Y , Oyama T , et al. Analgesic effect of benzoylmesaconine.[J]. Folia Pharmacologica Japonica, 1993, 102(6):399-404. Chen L, Zhang C, Cao J, et al. Yiyi Fuzi Baijiang Decoction Alleviates Ulcerative Colitis Partly by Regulating TLR4-Mediated PI3K/Akt and NF-?B Pathways. Evidence-Based Complementary and Alternative Medicine. 2022, 2022.