TargetMol

UNC2025

Product Code:
 
TAR-T7007
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7007-2mg2mg£97.00
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TAR-T7007-5mg5mg£112.00
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TAR-T7007-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T7007-10mg10mg£139.00
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TAR-T7007-25mg25mg£172.00
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TAR-T7007-50mg50mg£237.00
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TAR-T7007-100mg100mg£367.00
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Further Information

Bioactivity:
UNC-2025? IC50 of 0.74 nM and 0.8 nM? is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
CAS:
1429881-91-3
Formula:
C28H40N6O
Molecular Weight:
476.669
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9974
SMILES:
CCCCNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(CN2CCN(C)CC2)cc1
Target:
FLT; TAM Receptor

References

Cummings CT, et al. Mol Cancer Ther. 2015, 14(9), 2014-2022. Zhang W, et al. J Med Chem. 2014, 57(16), 7031-7041.