TargetMol

Endomorphin 2

Product Code:
 
TAR-T7218
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7218-1mg1mg£103.00
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TAR-T7218-2mg2mg£115.00
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TAR-T7218-5mg5mg£130.00
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TAR-T7218-10mg10mg£169.00
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TAR-T7218-25mg25mg£285.00
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TAR-T7218-50mg50mg£338.00
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TAR-T7218-100mg100mg£470.00
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Further Information

Bioactivity:
Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers form symmetric synaptic connections with motoneurons innervating skeletal muscles of the lower limbs in lamina IX of the spinal ventral horn and EM-2 might exert inhibitory effects on the activities of these motoneurons through both presynaptic and postsynaptic mechanisms.
CAS:
141801-26-5
Formula:
C32H37N5O5
Molecular Weight:
571.678
Pathway:
GPCR/G Protein; Endocrinology/Hormones; Neuroscience
Purity:
0.98
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Target:
Opioid Receptor

References

Zhen-Yu W , Ya-Cheng L , Ban F , et al. Endomorphin-2 Decreases Excitatory Synaptic Transmission in the Spinal Ventral Horn of the Rat[J]. Frontiers in Neural Circuits, 2017, 11:55-.