TargetMol

Gemigliptin

Product Code:
 
TAR-T7369
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7369-2mg2mg£98.00
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TAR-T7369-5mg5mg£115.00
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TAR-T7369-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T7369-10mg10mg£142.00
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TAR-T7369-25mg25mg£198.00
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TAR-T7369-50mg50mg£289.00
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TAR-T7369-100mg100mg£414.00
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TAR-T7369-500mg500mg£849.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Gemigliptin is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)
CAS:
911637-19-9
Formula:
C18H19F8N5O2
Molecular Weight:
489.36
Pathway:
Proteases/Proteasome; Ubiquitination
Purity:
0.98
SMILES:
N[C@H](CN1CC(F)(F)CCC1=O)CC(=O)N1CCc2c(C1)nc(nc2C(F)(F)F)C(F)(F)F
Target:
Proteasome; DPP-4

References

Jung, Beom, Seo, et al. Gemigliptin Attenuates Renal Fibrosis Through Down-Regulation of the NLRP3 Inflammasome.[J]. Diabetes & metabolism journal, 2019. Choi S Y , Ryu H M , Oh E J , et al. Dipeptidyl peptidase-4 inhibitor gemigliptin protects against vascular calcification in an experimental chronic kidney disease and vascular smooth muscle cells[J]. PLoS ONE, 2017, 12(7):e0180393.