TargetMol

WT-161

Product Code:
 
TAR-T7385
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7385-1mg1mg£99.00
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TAR-T7385-2mg2mg£112.00
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TAR-T7385-5mg5mg£136.00
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TAR-T7385-1mL1 mL * 10 mM (in DMSO)£139.00
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TAR-T7385-10mg10mg£168.00
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TAR-T7385-25mg25mg£237.00
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TAR-T7385-50mg50mg£319.00
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TAR-T7385-100mg100mg£446.00
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This product comes from: United States.
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Further Information

Bioactivity:
WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM).
CAS:
1206731-57-8
Formula:
C27H30N4O3
Molecular Weight:
458.562
Pathway:
Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.9709
SMILES:
ONC(=O)CCCCCCC(=O)NN=Cc1ccc(cc1)N(c1ccccc1)c1ccccc1
Target:
Apoptosis; HDAC

References

Hideshima T , Qi J , Paranal R M , et al. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma[J]. Proceedings of the National Academy of Sciences, 2016:201608067. Hideshima T, Mazitschek R, Qi J,et al.HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer[J].Oncotarget. 2017 Jul 5;8(46):80109-80123.