TargetMol

SAR407899

Product Code:
 
TAR-T7391
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7391-2mg2mg£97.00
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TAR-T7391-5mg5mg£112.00
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TAR-T7391-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T7391-10mg10mg£139.00
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TAR-T7391-25mg25mg£193.00
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TAR-T7391-50mg50mg£269.00
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Quantity:
TAR-T7391-100mg100mg£386.00
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This product comes from: United States.
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Further Information

Bioactivity:
SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.
CAS:
923359-38-0
Formula:
C14H16N2O2
Molecular Weight:
244.294
Pathway:
Stem Cells; Cell Cycle/Checkpoint; Cytoskeletal Signaling
Purity:
0.9991
SMILES:
O=c1[nH]ccc2cc(OC3CCNCC3)ccc12
Target:
ROCK; Rho

References

Grisk O, Schl?ter T, Reimer N, et al.The Rho kinase inhibitor SAR407899 potently inhibits endothelin-1-induced constriction of renal resistance arteries[J].J Hypertens. 2012 May;30(5):980-9. Guagnini F , Ferazzini M , Grasso M , et al. Erectile properties of the Rho-kinase inhibitor SAR407899 in diabetic animals and human isolated corpora cavernosa[J]. Journal of Translational Medicine, 2012, 10(1):59-0.