TargetMol

ONO-7300243

Product Code:
 
TAR-T7393
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7393-1mg1mg£101.00
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TAR-T7393-2mg2mg£114.00
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TAR-T7393-5mg5mg£141.00
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TAR-T7393-1mL1 mL * 10 mM (in DMSO)£143.00
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TAR-T7393-10mg10mg£189.00
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TAR-T7393-25mg25mg£334.00
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TAR-T7393-50mg50mg£529.00
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TAR-T7393-100mg100mg£728.00
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Further Information

Bioactivity:
ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).
CAS:
638132-34-0
Formula:
C28H31NO5
Molecular Weight:
461.558
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
COc1cc(cc(OC)c1C)C(=O)N(CCCc1ccccc1)Cc1ccc(CC(O)=O)cc1
Target:
LPA Receptor; LPL Receptor

References

Terakado M , Suzuki H , Hashimura K , et al. Discovery of a Slow Tight Binding LPA1 Antagonist (ONO-0300302) for the Treatment of Benign Prostatic Hyperplasia[J]. ACS Medicinal Chemistry Letters, 2017:acsmedchemlett.7b00383. Terakado M , Suzuki H , Hashimura K , et al. Discovery of ONO-7300243 from a novel class of Lysophosphatidic Acid Receptor 1 antagonists: From hit to lead.[J]. ACS Medicinal Chemistry Letters, 2016:acsmedchemlett.6b00225.