TargetMol

RRX-001

Product Code:
 
TAR-T7400
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7400-1mg1mg£109.00
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TAR-T7400-2mg2mg£127.00
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TAR-T7400-5mg5mg£164.00
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TAR-T7400-1mL1 mL * 10 mM (in DMSO)£174.00
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TAR-T7400-10mg10mg£195.00
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TAR-T7400-25mg25mg£306.00
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TAR-T7400-50mg50mg£483.00
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TAR-T7400-100mg100mg£671.00
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Quantity:
TAR-T7400-500mg500mg£1,324.00
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This product comes from: United States.
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Further Information

Bioactivity:
RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity
CAS:
925206-65-1
Formula:
C5H6BrN3O5
Molecular Weight:
268.023
Pathway:
Apoptosis; Microbiology/Virology; Metabolism
Purity:
0.98
SMILES:
[O-][N+](=O)C1(CN(C1)C(=O)CBr)[N+]([O-])=O
Target:
Apoptosis; Dehydrogenase; Parasite

References

Gong M, Huang Y, Feng H, et al.A nanodrug combining CD47 and sonodynamic therapy efficiently inhibits osteosarcoma deterioration.Journal of Controlled Release.2023, 355: 68-84. Oronsky B , Paulmurugan R , Foygel K , et al. RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials[J]. Expert Opinion on Investigational Drugs, 2017, 26(1):109-119. Zhao H , Ning S , Nolley R , et al. The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry[J]. Clinical Epigenetics, 2017, 9(1):4.