TargetMol

SRT 1460

Product Code:
 
TAR-T8346
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8346-2mg2mg£115.00
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TAR-T8346-5mg5mg£134.00
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Quantity:
TAR-T8346-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T8346-10mg10mg£165.00
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TAR-T8346-25mg25mg£213.00
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Quantity:
TAR-T8346-50mg50mg£283.00
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Quantity:
TAR-T8346-100mg100mg£389.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SRT1460 is a SIRT1 activator.
CAS:
925432-73-1
Formula:
C26H29N5O4S
Molecular Weight:
507.61
Pathway:
Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.9762
SMILES:
COc1cc(cc(OC)c1OC)C(=O)Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1
Target:
Sirtuin

References

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.J Biol Chem. 2010 Mar 12;285(11):8340-51.Pacholec M, Bleasdale JE, Chrunyk B,et al. Chini CC, Espindola-Netto JM, Mondal G,et al. SIRT1-Activating Compounds (STAC) Negatively Regulate Pancreatic Cancer Cell Growth and Viability Through a SIRT1 Lysosomal-Dependent Pathway[J]. clinical cancer research, 2016, 22(10):2496-2507.