TargetMol

Alectinib hydrochloride

Product Code:
 
TAR-T8387
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8387-10mg10mg£111.00
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TAR-T8387-25mg25mg£132.00
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TAR-T8387-50mg50mg£149.00
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TAR-T8387-100mg100mg£201.00
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This product comes from: United States.
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Further Information

Bioactivity:
Alectinib hydrochloride is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)
CAS:
1256589-74-8
Formula:
C30H35ClN4O2
Molecular Weight:
519.09
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9996
SMILES:
Cl.CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCC(CC1)N1CCOCC1
Target:
ALK

References

Julia P , Sohita D . Alectinib: A Review in Advanced, ALK-Positive NSCLC[J]. Drugs, 2018. Sakamoto H, et al. CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant. Cancer Cell. 2011, 19(5), 679-690.