TargetMol

RET V804M-IN-1

Product Code:
 
TAR-T8467
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8467-1mg1mg£96.00
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TAR-T8467-2mg2mg£107.00
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TAR-T8467-5mg5mg£128.00
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TAR-T8467-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T8467-10mg10mg£148.00
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TAR-T8467-25mg25mg£205.00
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TAR-T8467-50mg50mg£282.00
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TAR-T8467-100mg100mg£369.00
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TAR-T8467-200mg200mg£511.00
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Further Information

Bioactivity:
RET V804M-IN-1 is a wt-RET -selective RETV804M kinase inhibitors(IC50 = 20 nM).
CAS:
2414909-94-5
Formula:
C19H16N6O
Molecular Weight:
344.378
Pathway:
Tyrosine Kinase/Adaptors; Apoptosis
Purity:
0.9962
SMILES:
NC(=O)c1ccc(cc1)-c1cnn2ccc(NCc3cccnc3)nc12
Target:
c-RET

References

Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET V804M Kinase. ACS Med Chem Lett. 2020 Feb 28;11(4):497-505.