TargetMol

JSH-150

Product Code:
 
TAR-T8484
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8484-5mg5mg£144.00
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Quantity:
TAR-T8484-10mg10mg£197.00
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Quantity:
TAR-T8484-25mg25mg£351.00
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Quantity:
TAR-T8484-50mg50mg£503.00
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Quantity:
TAR-T8484-100mg100mg£593.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).
CAS:
2247481-21-4
Formula:
C24H33ClN6O2S
Molecular Weight:
505.08
Pathway:
Cell Cycle/Checkpoint
Purity:
0.9996
SMILES:
COCCN[C@H]1CC[C@@H](CC1)Nc1cc(-c2csc(NCC3(CCOCC3)C#N)n2)c(Cl)cn1
Target:
CDK

References

Beilei Wang, et al. Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor. Eur J Med Chem. 13 September 2018.