TargetMol

NDMC101

Product Code:
 
TAR-T8550
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8550-2mg2mg£101.00
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TAR-T8550-5mg5mg£119.00
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TAR-T8550-1mL1 mL * 10 mM (in DMSO)£121.00
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TAR-T8550-10mg10mg£152.00
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TAR-T8550-25mg25mg£237.00
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TAR-T8550-50mg50mg£334.00
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TAR-T8550-100mg100mg£464.00
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TAR-T8550-500mg500mg£946.00
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This product comes from: United States.
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Further Information

Bioactivity:
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.
CAS:
1308631-40-4
Formula:
C13H9ClFNO2
Molecular Weight:
265.67
Pathway:
Proteases/Proteasome; ; Ubiquitination; NF-κb
Purity:
0.9959
SMILES:
Oc1ccccc1C(=O)Nc1ccc(Cl)cc1F
Target:
NF-κB; Proteasome

References

Jun-Ting Liou, et al. A salicylate-based small molecule HS-Cm exhibits immunomodulatory effects and inhibits dipeptidyl peptidase-IV activity in human T cells. Eur J Pharmacol. 2014 Mar 5;726:124-32. Cheng C P , Huang H S , Hsu Y C , et al. A benzamide-linked small molecule NDMC101 inhibits NFATc1 and NF-?B activity: a potential osteoclastogenesis inhibitor for experimental arthritis.[J]. Journal of Clinical Immunology, 2012, 32(4):762-777.