TargetMol

UAMC-3203 hydrochloride

Product Code:
 
TAR-T8662
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8662-2mg2mg£107.00
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TAR-T8662-5mg5mg£128.00
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TAR-T8662-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T8662-10mg10mg£161.00
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TAR-T8662-25mg25mg£209.00
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TAR-T8662-50mg50mg£242.00
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TAR-T8662-100mg100mg£309.00
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TAR-T8662-200mg200mg£426.00
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This product comes from: United States.
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Further Information

Bioactivity:
UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
CAS:
2271358-65-5
Formula:
C25H38ClN5O2S
Molecular Weight:
508.12
Pathway:
Apoptosis; Cell Cycle/Checkpoint
Purity:
0.9987
SMILES:
Cl.O=S(=O)(NCCN1CCNCC1)c1ccc(NC2CCCCC2)c(NCc2ccccc2)c1
Target:
Ferroptosis

References

Yan B, Ai Y, Sun Q, et al. Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1. Molecular Cell. 2020 Yan B, Ai Y, Sun Q, et al. Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1[J]. Molecular Cell. 2020 Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140.