TargetMol

MSAB

Product Code:
 
TAR-T8710
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8710-2mg2mg£104.00
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TAR-T8710-5mg5mg£124.00
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TAR-T8710-1mL1 mL * 10 mM (in DMSO)£131.00
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TAR-T8710-10mg10mg£168.00
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TAR-T8710-25mg25mg£269.00
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TAR-T8710-50mg50mg£369.00
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TAR-T8710-100mg100mg£523.00
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TAR-T8710-500mg500mg£1,018.00
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Further Information

Bioactivity:
MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.
CAS:
173436-66-3
Formula:
C15H15NO4S
Molecular Weight:
305.35
Pathway:
Stem Cells; Cytoskeletal Signaling
Purity:
0.9967
SMILES:
COC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1
Target:
Wnt/beta-catenin

References

Hwang SY, et, al. Direct Targeting of ?-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/?-Catenin Signaling. Cell Rep. 2016 Jun 28;16(1):28-36.