TargetMol

ERK-IN-3

Product Code:
 
TAR-T9141
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9141-10mg10mgEnquire
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TAR-T9141-50mg50mgEnquire
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TAR-T9141-1mg1mg£115.00
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TAR-T9141-2mg2mg£134.00
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TAR-T9141-5mg5mg£172.00
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TAR-T9141-1mL1 mL * 10 mM (in DMSO)£177.00
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Further Information

Bioactivity:
ERK-IN-3 is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.
CAS:
2055597-12-9
Formula:
C22H25ClFN7O2
Molecular Weight:
473.94
Pathway:
MAPK
Purity:
0.9976
SMILES:
Cc1cnc(NC2CCOCC2)nc1-n1cnc(c1)C(=O)N[C@H](CN)c1cc(F)cc(Cl)c1
Target:
ERK

References

Sanjeeva PR, et, al. Abstract B150: ASN007, a novel oral ERK inhibitor, shows robust antitumor activity in RAS mutant cancer models. Molecular Cancer Therapeutics. 2018 Jan; 17(1).