TargetMol

MAP4343

Product Code:
 
TAR-T9504
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9504-1mg1mg£98.00
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TAR-T9504-2mg2mg£109.00
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TAR-T9504-5mg5mg£135.00
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TAR-T9504-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T9504-10mg10mg£182.00
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TAR-T9504-25mg25mg£301.00
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TAR-T9504-50mg50mg£450.00
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TAR-T9504-100mg100mg£627.00
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Further Information

Bioactivity:
Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of neurons from neurotoxic agents.
CAS:
511-26-2
Formula:
C44H67O4
Molecular Weight:
660
Pathway:
Cytoskeletal Signaling
Purity:
0.9932
SMILES:
C[C@](CC1)([C@@H](CC2)[C@H]3[C@H]1[C@@](C)(CC[C@@H](C1)OC)C1=CC3)[C@H]2C(C)=OC[C@](CC1)([C@@H](CC2)[C@H]3[C@H]1[C@@](C)(CC[C@@H](C1)OC)C1=CC3)[C@H]2C(C)=O
Target:
Microtubule Associated

References

Fontaine-Lenoir V, et, al. Microtubule-associated protein 2 (MAP2) is a neurosteroid receptor. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4711-6. Duchossoy Y, et, al. Treatment of experimental spinal cord injury with 3?-methoxy-pregnenolone. Brain Res. 2011 Jul 27;1403:57-66.