TargetMol

T-1095

Product Code:
 
TAR-T9590
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9590-1mg1mg£109.00
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TAR-T9590-2mg2mg£125.00
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TAR-T9590-5mg5mg£148.00
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TAR-T9590-1mL1 mL * 10 mM (in DMSO)£180.00
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TAR-T9590-10mg10mg£182.00
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TAR-T9590-25mg25mg£254.00
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TAR-T9590-50mg50mg£401.00
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TAR-T9590-100mg100mg£544.00
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This product comes from: United States.
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Further Information

Bioactivity:
T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).
CAS:
209746-59-8
Formula:
C26H28O11
Molecular Weight:
516.499
Pathway:
Metabolism; GPCR/G Protein
Purity:
0.9956
SMILES:
COC(=O)OC[C@H]1O[C@@H](Oc2cc(C)cc(O)c2C(=O)CCc2ccc3occc3c2)[C@H](O)[C@@H](O)[C@@H]1O
Target:
SGLT; transporter

References

Nunoi K, et al. Beneficial effect of T-1095, a selective inhibitor of renal Na+-glucose cotransporters, on metabolic index and insulin secretion in spontaneously diabetic GK rats. Clin Exp Pharmacol Physiol. 2002 May-Jun;29(5-6):386-90. Adachi T, et al. T-1095, a renal Na+-glucose transporter inhibitor, improves hyperglycemia in streptozotocin-induced diabetic rats. Metabolism. 2000 Aug;49(8):990-5.