TargetMol

ZINC05007751

Product Code:
 
TAR-T9880
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9880-1mg1mg£111.00
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TAR-T9880-2mg2mg£130.00
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TAR-T9880-5mg5mg£168.00
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TAR-T9880-1mL1 mL * 10 mM (in DMSO)£197.00
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TAR-T9880-10mg10mg£229.00
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TAR-T9880-25mg25mg£369.00
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TAR-T9880-50mg50mg£550.00
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TAR-T9880-100mg100mg£755.00
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Further Information

Bioactivity:
ZINC05007751 is an effective inhibitor of NIMA-related kinase NEK6 (IC50 = 3.4 μM). ZINC05007751 is very selective against NEK1 and NEK6 with no significant activity observed against NEK2, NEK7, and NEK9.
CAS:
591239-68-8
Formula:
C18H12N2O3
Molecular Weight:
304.305
Pathway:
MAPK
Purity:
0.9712
SMILES:
CC1=C(C#N)C(O)=NC(=O)C1=C/c1ccc(o1)-c1ccccc1
Target:
MAPK

References

De Donato M, et al. Identification and antitumor activity of a novel inhibitor of the NIMA-related kinase NEK6. Sci Rep. 2018;8(1):16047. Published 2018 Oct 30.