TargetMol

3-demethylcolchicine

Product Code:
 
TAR-TN6706
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN6706-2mg2mg£108.00
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TAR-TN6706-5mg5mg£130.00
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TAR-TN6706-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-TN6706-10mg10mg£164.00
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TAR-TN6706-25mg25mg£256.00
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TAR-TN6706-50mg50mg£359.00
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This product comes from: United States.
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Further Information

Bioactivity:
3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.
CAS:
7336-33-6
Formula:
C21H23NO6
Molecular Weight:
385.416
Pathway:
Immunology/Inflammation; NF-κb; Metabolism
Purity:
0.9941
SMILES:
COc1c(O)cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c1OC
Target:
Reactive Oxygen Species

References

M R?sner, H G Capraro, A E Jacobson.et al. Biological effects of modified colchicines. Improved preparation of 2-demethylcolchicine, 3-demethylcolchicine, and (+)-colchicine and reassignment of the position of the double bond in dehydro-7-deacetamidocolchicines.J Med Chem. 1981 Mar;24(3):257-61.