TargetMol

Polymyxin B nonapeptide acetate

Product Code:
 
TAR-TP1341L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-TP1341L-1mg1mg£124.00
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TAR-TP1341L-2mg2mg£147.00
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TAR-TP1341L-5mg5mg£181.00
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TAR-TP1341L-10mg10mg£254.00
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TAR-TP1341L-25mg25mg£475.00
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TAR-TP1341L-50mg50mg£659.00
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Quantity:
TAR-TP1341L-100mg100mg£863.00
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Further Information

Bioactivity:
Polymyxin B nonapeptide acetate is a cationic cyclic peptide. Polyxin B nonapeptide is a derivative produced by enzymatic cleavage of polyxin B. Compared with polyxin B, polyxin B nonapeptide has low toxicity, lacks bactericidal activity and still has the ability to destroy the outer membrane of Gram-negative bacteria.
CAS:
TP1341L
Formula:
C45H78N14O13
Molecular Weight:
1023.19
Pathway:
Microbiology/Virology
Purity:
0.9855
SMILES:
C[C@@H](O)[C@H]1C(NCC[C@H](NC([C@@H](NC([C@@H](N)[C@H](O)C)=O)CCN)=O)C(N[C@@H](CCN)C(N[C@H](CC2=CC=CC=C2)C(N[C@@H](CC(C)C)C(N[C@@H](CCN)C(N[C@@H](CCN)C(N1)=O)=O)=O)=O)=O)=O)=O.CC(O)=O
Target:
Antibacterial; Antibiotic

References

Tsubery H , Ofek I , Cohen S , et al. Structure-function studies of polymyxin B nonapeptide: implications to sensitization of gram-negative bacteria.[J]. Journal of Medicinal Chemistry, 2000, 43(16):3085-3092. Ofek I , Cohen S , Rahmani R , et al. Antibacterial synergism of polymyxin B nonapeptide and hydrophobic antibiotics in experimental gram-negative infections in mice.[J]. Antimicrobial Agents and Chemotherapy, 1994, 38(2):374-377.