TargetMol

GPLGIAGQ acetate

Product Code:
 
TAR-TP1535L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-TP1535L-1mg1mg£109.00
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TAR-TP1535L-2mg2mg£124.00
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TAR-TP1535L-5mg5mg£147.00
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TAR-TP1535L-10mg10mg£181.00
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TAR-TP1535L-25mg25mg£258.00
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TAR-TP1535L-50mg50mg£325.00
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TAR-TP1535L-100mg100mg£454.00
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TAR-TP1535L-500mg500mg£946.00
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This product comes from: United States.
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Further Information

Bioactivity:
GPLGIAGQ acetate is a MMP2-cleavable polypeptide. GPLGIAGQ acetate can be used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy.
CAS:
0
Formula:
C33H57N9O12
Molecular Weight:
771.86
Pathway:
Proteases/Proteasome
Purity:
0.98
SMILES:
C[C@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H]1CCCN1C(CN)=O)=O)CC(C)C)=O)=O)[C@@H](C)CC)=O)C(NCC(N[C@H](C(O)=O)CCC(N)=O)=O)=O.CC(O)=O
Target:
MMP

References

Liu FH, et al. Enzyme-sensitive cytotoxic peptide-dendrimer conjugates enhance cell apoptosis and deep tumor penetration. Biomater Sci. 2018 Feb 27;6(3):604-613. Hou W, et al. MMP2-Targeting and Redox-Responsive PEGylated Chlorin e6 Nanoparticles for Cancer Near-Infrared Imaging and Photodynamic Therapy. ACS Appl Mater Interfaces. 2016 Jan 20;8(2):1447-57. Zhu L, et al. Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs. Biomaterials. 2014 Apr;35(13):4213-22.