TargetMol

ACY-775

Product Code:
 
TAR-TQ0074
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0074-1mg1mg£95.00
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TAR-TQ0074-2mg2mg£105.00
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TAR-TQ0074-5mg5mg£128.00
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TAR-TQ0074-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-TQ0074-10mg10mg£168.00
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TAR-TQ0074-25mg25mg£275.00
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TAR-TQ0074-50mg50mg£402.00
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TAR-TQ0074-100mg100mg£567.00
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TAR-TQ0074-500mg500mg£1,139.00
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Further Information

Bioactivity:
ACY-775 is an effective and specific inhibitor of HDAC6 (IC50: 7.5 nM).
CAS:
1375466-18-4
Formula:
C17H19FN4O2
Molecular Weight:
330.363
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9767
SMILES:
ONC(=O)c1cnc(NC2(CCCCC2)c2cccc(F)c2)nc1
Target:
HDAC

References

Jeanine Jochems et al. Antidepressant-Like Properties of Novel HDAC6-Selective Inhibitors with Improved Brain Bioavailability. Neuropsychopharmacology. 2014 Jan; 39(2): 389-400. Veronick Benoy, et al. Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot-Marie-Tooth Disease. Neurotherapeutics. 2017 Apr; 14(2): 417-428.