TargetMol

VCH-916

Product Code:
 
TAR-TQ0122
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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Further Information

Bioactivity:
VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.
CAS:
1200133-34-1
Formula:
C26H36KNO4S
Molecular Weight:
497.74
Pathway:
Microbiology/Virology; Proteases/Proteasome
Purity:
0.98
SMILES:
[K+].COC1CCC(CC1)N(C(=O)C1CCC(C)CC1)c1cc(sc1C([O-])=O)C1=CCCCC1
Target:
HCV Protease

References

Pierre L Beaulieu. Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection. Informahealthcare. 2009, 19(2): 145-164 Abdelrahman S. Mayhoub. Hepatitis C RNA-dependent RNA polymerase inhibitors: A review of structure-activity and resistance relationships; different scaffolds and mutations. Bioorganic & Medicinal Chemistry. 2012, 20 (10): 3150-3161. Debasis Dasa, Jian Honga, Shu-Hui Chena, et al. Recent advances in drug discovery of benzothiadiazine and related analogs as HCV NS5B polymerase inhibitors. Bioorganic & Medicinal Chemistry. 2011, 19(16): 4690-4703