TargetMol

SR-3677

Product Code:
 
TAR-TQ0187
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0187-2mg2mg£104.00
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TAR-TQ0187-5mg5mg£125.00
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TAR-TQ0187-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-TQ0187-10mg10mg£152.00
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TAR-TQ0187-25mg25mg£217.00
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TAR-TQ0187-50mg50mg£340.00
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This product comes from: United States.
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Further Information

Bioactivity:
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).
CAS:
1072959-67-1
Formula:
C22H24N4O4
Molecular Weight:
408.458
Pathway:
Stem Cells; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Autophagy
Purity:
0.9991
SMILES:
CN(C)CCOc1cc(ccc1NC(=O)C1COc2ccccc2O1)-c1cn[nH]c1
Target:
ROCK; Autophagy

References

Feng Y, et al. Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors. J Med Chem. 2008 Nov 13;51(21):6642-5.