TargetMol

R1530

Product Code:
 
TAR-TQ0317
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-TQ0317-1mg1mg£109.00
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TAR-TQ0317-2mg2mg£125.00
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TAR-TQ0317-5mg5mg£161.00
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TAR-TQ0317-10mg10mg£209.00
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TAR-TQ0317-25mg25mg£349.00
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TAR-TQ0317-50mg50mg£546.00
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TAR-TQ0317-100mg100mg£755.00
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This product comes from: United States.
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Further Information

Bioactivity:
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
CAS:
882531-87-5
Formula:
C18H14ClFN4O
Molecular Weight:
356.79
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9796
SMILES:
COc1cc2N=C3NNC(C)=C3N=C(c3ccccc3Cl)c2cc1F
Target:
VEGFR; FGFR; FLT; PDGFR

References

Kolinsky K, et al. Preclinical evaluation of the novel multi-targeted agent R1530. Cancer Chemother Pharmacol. 2011 Dec;68(6):1585-94. Tovar C, et al. Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy. Cell Cycle. 2010 Aug 15;9(16):3364-75.