TargetMol

Oxantel

Product Code:
 
TAR-T0323L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T0323L-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
Oxantel is a fumarate reductase inhibitor with anthelmintic activity.
CAS:
36531-26-7
Formula:
C13H16N2O
Molecular Weight:
216.284
Purity:
0.98
SMILES:
CN1CCCN=C1C=Cc1cccc(O)c1

References

1. Cowan N, Meier C, Neodo A, Keiser J. Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes. Int J Parasitol Drugs Drug Resist. 2017 Mar 24;7(2):159-173. doi: 10.1016/j.ijpddr.2017.03.005. [Epub ahead of print] PubMed PMID: 28371660; PubMed Central PMCID: PMC5377441. 2. Cowan N, Vargas M, Keiser J. In Vitro and In Vivo Drug Interaction Study of Two Lead Combinations, Oxantel Pamoate plus Albendazole and Albendazole plus Mebendazole, for the Treatment of Soil-Transmitted Helminthiasis. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6127-33. doi: 10.1128/AAC.01217-16. Print 2016 Oct. PubMed PMID: 27480864; PubMed Central PMCID: PMC5038309. 3. Abongwa M, Buxton SK, Courtot E, Charvet CL, Neveu C, McCoy CJ, Verma S, Robertson AP, Martin RJ. Pharmacological profile of Ascaris suum ACR-16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues. Br J Pharmacol. 2016 Aug;173(16):2463-77. doi: 10.1111/bph.13524. Epub 2016 Jul 18. PubMed PMID: 27238203; PubMed Central PMCID: PMC4959957. 4. Speich B, Moser W, Ali SM, Ame SM, Albonico M, Hattendorf J, Keiser J. Efficacy and reinfection with soil-transmitted helminths 18-weeks post-treatment with albendazole-ivermectin, albendazole-mebendazole, albendazole-oxantel pamoate and mebendazole. Parasit Vectors. 2016 Mar 2;9:123. doi: 10.1186/s13071-016-1406-8. PubMed PMID: 26935065; PubMed Central PMCID: PMC4776366.