TargetMol

PF-592379

Product Code:
 
TAR-T10080
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10080-5mg5mg£850.00
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Quantity:
TAR-T10080-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T10080-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
PF-592379 is a potent agonist of dopamine D3 receptor (EC50: 21 nM).
CAS:
710655-15-5
Formula:
C13H21N3O
Molecular Weight:
235.331
Purity:
0.98
SMILES:
CCCN1C[C@H](OC[C@@H]1C)c1ccc(N)nc1

References

1. Attkins N, et al. Pharmacokinetics and elucidation of the rates and routes of N-glucuronidation of PF-592379, an oral dopamine 3 agonist in rat, dog, and human. Xenobiotica. 2010 Nov;40(11):730-42. 2. Wager TT, et al. Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects. ACS Chem Neurosci. 2017 Jan 18;8(1):165-177. 3. Collins GT, et al. Lack of abuse potential in a highly selective dopamine D3 agonist, PF-592,379, in drug self-administration and drug discrimination in rats. Behav Pharmacol. 2012 Jun;23(3):280-91.