TargetMol

PSN-GK1

Product Code:
 
TAR-T10092
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10092-5mg5mg£850.00
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TAR-T10092-50mg50mg£1,661.00
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Quantity:
TAR-T10092-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
PSN-GK1 is a potent activator of glucokinase (EC50: 0.13 μM).
CAS:
745051-61-0
Formula:
C20H23FN2O4S2
Molecular Weight:
438.53
Purity:
0.98
SMILES:
Fc1cnc(NC(=O)[C@H](CC2CCOCC2)c2ccc(cc2)S(=O)(=O)C2CC2)s1

References

1. Bertram LS, et al. SAR, pharmacokinetics, safety, and efficacy of glucokinase activating 2-(4-sulfonylphenyl)-N-thiazol-2-ylacetamides: discovery of PSN-GK1. J Med Chem. 2008 Jul 24;51(14):4340-5. 2. Fyfe MC, et al. Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions. Diabetologia. 2007 Jun;50(6):1277-87.