TargetMol

AZ-3

Product Code:
 
TAR-T10424
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T10424-5mg5mg£1,412.00
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Quantity:
TAR-T10424-50mg50mg£2,785.00
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Quantity:
TAR-T10424-100mg100mg£3,765.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
CAS:
2228908-91-4
Formula:
C20H28FN7
Molecular Weight:
385.491
Pathway:
Angiogenesis; Stem Cells; JAK/STAT signaling; Chromatin/Epigenetic
Purity:
0.98
SMILES:
CC[C@@H](C)Nc1nc(Nc2cc(cnc2F)N2C[C@@H]3C[C@H]2CN3C)ncc1C
Target:
JAK

References

1. Grimster NP, et al. Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors. J Med Chem. 2018 Jun 28;61(12):5235-5244.