TargetMol

BR351

Product Code:
 
TAR-T10597
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10597-5mg5mg£930.00
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Quantity:
TAR-T10597-50mg50mg£1,821.00
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Quantity:
TAR-T10597-100mg100mg£2,319.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
CAS:
960113-85-3
Formula:
C20H25FN2O5S
Molecular Weight:
424.49
Pathway:
Proteases/Proteasome
Purity:
0.98
SMILES:
CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCF)cc1)C(=O)NO
Target:
MMP

References

1. Wagner S, et al. Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET. J Med Chem. 2007 Nov 15;50(23):5752-64.