TargetMol

c-Fms-IN-9

Product Code:
 
TAR-T10648
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10648-5mg5mg£930.00
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Quantity:
TAR-T10648-50mg50mg£1,821.00
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Quantity:
TAR-T10648-100mg100mg£2,319.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1 (Example 7). It inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT (IC50s: <0.01 μM and 0.1-1 μM).
CAS:
1628574-50-4
Formula:
C21H23N7O2
Molecular Weight:
405.462
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
Cc1nc(ccc1Oc1ccnc(c1)-c1cnn(C)c1)-n1[nH]c(nc1=O)C(C)(C)C
Target:
c-Fms

References

1. Gary E. L. BRANDT, et al. 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145023A1.