TargetMol

CB1151

Product Code:
 
TAR-T10695
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10695-5mg5mg£870.00
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This product comes from: United States.
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Further Information

Bioactivity:
CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 with anti-tumor effects. It inhibits MCF-7 cell growth (IC50: 0.82 nM).
CAS:
182369-28-4
Formula:
C28H46O4
Molecular Weight:
446.672
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H]([C@@H](C)OCCC(O)(CC)CC)[C@@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C

References

1. M?rk Hansen C, et al. The potent anti-proliferative effect of 20-epi analogues of 1,25 dihydroxyvitamin D3 in human breast-cancer MCF-7 cells is related to promoter selectivity.Int J Cancer. 1996 Sep 4;67(5):739-42. 2. Nayeri S, et al. High-affinity nuclear receptor binding of 20-epi analogues of 1,25-dihydroxyvitamin D3 correlates well with gene activation.J Cell Biochem. 1996 Sep 1;62(3):325-33.